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COMPLEMENT C3B INACTIVATOR PROTEINS
Descriptors Found:
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DeCS
Descriptor
English
:
Complement C3b Inactivator Proteins
Descriptor
Spanish
:
Proteínas Inactivadoras del Complemento C3b
Descriptor
Portuguese
:
Proteínas Inativadoras do Complemento C3b
Tree Number:
D12.776.124.486.274.920.325
Definition
English
:
Endogenous
proteins
that inhibit or inactivate
COMPLEMENT C3B
. They include
COMPLEMENT FACTOR H
and
COMPLEMENT FACTOR I
(C3b/C4b inactivator). They cleave or promote the cleavage of C3b into inactive fragments, and thus are important in the
down-regulation
of
COMPLEMENT ACTIVATION
and its cytolytic sequence.
Indexing Annotation
English
:
DF: C3B INACT
Pharmacological Action:
Complement Inactivating Agents
History Note
English
:
2006 (1978)
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
22142
Unique Identifier:
D003180
Occurrence in VHL
:
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